ESTROGEN, THROUGH ESTROGEN RECEPTOR 1, REGULATES HISTONE MODIFICATIONS AND CHROMATIN REMODELING DURING SPERMATOGENESIS IN ADULT RATS

Estrogen, through estrogen receptor 1, regulates histone modifications and chromatin remodeling during spermatogenesis in adult rats

Estrogen receptors (ESR1 and ESR2) play crucial roles in various processes during spermatogenesis.To elucidate individual roles of ESRs in male fertility, we developed in vivo selective ESR agonist administration models.Adult male rats treated with ESR1 and ESR2 agonist for 60 days show spermatogenic defects leading to reduced sperm counts and fert

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The reputational and ethical consequences of deceptive chatbot use

Abstract The use of chatbots is becoming widespread as they offer significant economic opportunities.At the same time, however, customers seem to prefer interacting with human operators when making inquiries and as a result are not as cooperative with chatbots when their use is known.This specific situation creates an incentive for organizations to

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Franchising As Hybrid Organization: Russian Skill

Russia has favorable conditions for development of hybrid cooperation (franchising) on the different markets.On the one hand, as well as for the majority of countries with transition economies many Russian markets has been undersaturated.On the other hand, as for the developed countries, Russia has highly skilled human resources and the developed s

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